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Metronidazole has shown proof of carcinogenic action in quite a few research involving Long-term oral administration in mice and rats. Outstanding among the consequences in the mouse was the marketing of pulmonary tumorigenesis. This is noticed in all six documented scientific studies in that species, like 1 research through which the animals ended up dosed on an intermittent plan (administration for the duration of each fourth 7 days only). At very high dose concentrations (close to five hundred mg/kg/working day), there was a statistically significant boost in the incidence of malignant liver tumors in males.

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The incidence of unique adverse reactions were not considerably distinctive amongst The 2 regimens. Unless of course percentages are if not stipulated, jnetoto the incidence of specific adverse reactions listed under was a lot less than 1%:

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